In December 1981, a petition was submitted to the Benton County, Missouri, clerk’s office to establish an ambulance district named the "Cole Camp Community Ambulance District." The proposed district's boundaries followed parts of Pettis and Benton counties, aligning with the Good Samaritan Nursing Home District, excluding the area covered by the Warsaw Lincoln Ambulance District. The district includes the municipalities of Cole Camp and Ionia. After a successful vote by the people, the district was created, initially funded through a $0.28 property tax. In April 2008, a half-cent sales tax was enacted, providing additional funding that enabled the district to hire paramedics and offer Advanced Life Support (ALS) services to the community.

The district spans approximately 320 square miles, covering the southeastern portion of Pettis County and most of northern Benton County. It serves a population of about 4,180, which can increase during the summer months due to seasonal traffic and lake visitors. The district averages around 600 calls annually and operates on an annual budget of approximately $500,000. In 2012, the station was rebuilt, featuring a 3,000 square-foot facility that houses two ambulances and serves as the base for the on-duty crew. In November of 2024 Voters passed an increase to the tax levy for 10 years of and additional $0.20. 

The district's Board of Directors consists of six members, with two elected each year to serve three-year terms. The Chief Administrator and Assistant Administrator are responsible for overseeing the operations of the district and managing its staff. The district employs three full-time EMTs and three full-time paramedics, who work a rotating 48-hour on shift schedule, followed by four days off and an additional shift off every seventh rotation, resulting in 10 days off. The district also employs between eight and ten part-time EMTs and paramedics, who assist with events, standbys, and covering open shifts. 

In recent years, the district has focused on improving the quality and outcomes of patient care. In January 2016, the district upgraded to Life Pack 15 Cardiac Monitors, bringing advanced technology to cardiac emergencies. In November 2016, the district acquired equipment that enables paramedics to transmit EKGs to local cardiac centers, activating cardiac catheterization teams to prepare for incoming emergencies. The district also purchased a commercial oxygen concentrator, allowing them to maintain their own oxygen supply and provide oxygen to surrounding first responder agencies. In May 2017, the district upgraded its mapping system to a GPS-guided version using data from Benton County 911. The district also uses iPads for patient reporting and a secure monitoring system within the ambulance to ensure the safety of both the patient and the crew. In July 2018, a new reporting software from ESO Solutions was purchased to enhance patient reporting and meet NEMSIS standards. In February 2019, the district took delivery of a new Type III Ford ambulance and upgraded its radio equipment to meet federal P25 standards, allowing communication with surrounding agencies during mutual aid calls and compatibility with the State of Missouri’s MOSWIN infrastructure. In 2023, the district expanded its communication capabilities by acquiring additional FCC licensing to operate its own P25-compliant radio system. The district continually strives to stay up-to-date with technology and equipment to provide the best possible care to patients.